1.
Org Biomol Chem
; 20(33): 6558-6561, 2022 08 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35900043
RESUMO
A diethylaminosulfur trifluoride (DAST)-mediated ring-opening reaction of cyclopropyl silyl ethers in nitriles produced allylic amides in moderate to good yields (up to 87%). Time course studies using ReactIR and O-isotopic labeling mechanistic studies suggested that the present reaction occurs via a Ritter-type process, leading to the formation of allylic amides.